Name | Sodium salicylate |
Synonyms | Sdium salicylate Sodium salicylate Sodium sallicylate salicylic acid sodium sodium salicylate usp Sodium salicylate BP98 SodiumSalicylatePurified SODIUM SALICYLATE, PH EUR Salicylic acid sodium salt o-hydroxybenzoic sodium salt 2-Hydroxybenzoic acid sodium salt Salicylic acid, sodium saltSodium SODIUM SALICYLATE R. G., REAG. PH. EUR. Sodium Salicylate 2-Hydroxybenzoic acid monosodium salt Sodium o-hydroxybenzoate |
CAS | 54-21-7 |
EINECS | 200-198-0 |
InChI | InChI=1/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1 |
InChIKey | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
Molecular Formula | C7H5NaO3 |
Molar Mass | 160.1 |
Density | 0.32 g/cm3 (20℃) |
Melting Point | >300 °C (lit.) |
Boling Point | 336.3°Cat760mmHg |
Water Solubility | 1000 g/L (20 ºC) |
Solubility | Soluble in water, glycerin, insoluble in ether, chloroform, benzene. |
Appearance | White crystal or powder |
Color | White |
Merck | 14,8332 |
BRN | 3732792 |
PH | 6.5 (100g/l, H2O, 20℃) |
Storage Condition | Store at +15°C to +25°C. |
Stability | Stable. Incompatible with mineral acids, metallic salts, iodine. May be light-sensitive. |
Sensitive | Light Sensitive |
MDL | MFCD00002440 |
Physical and Chemical Properties | Melting point 200°C. White scales or powder. Soluble in water (1:0.8,25 ° C) and glycerol (1:5), soluble in 95% ethanol (1:11), almost insoluble in ether, chloroform and benzene. The aqueous solution was slightly acidic (pH5-6). It turned pink in the long-lasting Dew Light. Odorless or microstrip special odor, sweet |
Use | Organic synthesis of raw materials, preservatives, determination of free acid in gastric juice reagent. Antipyretic analgesics and antirheumatic drugs. |
Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 1 |
RTECS | VO5075000 |
FLUKA BRAND F CODES | 8 |
TSCA | Yes |
HS Code | 29182100 |
Toxicity | LD50 i.p. in rats: 780 mg/kg (Goldenthal) |
EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
uses | organic synthesis raw materials, preservatives, reagents for measuring free acids in gastric juice. Antipyretic analgesics and antirheumatic drugs. antipyretic and analgesic, antirheumatic drugs, used for the treatment of active rheumatism, rheumatoid arthritis and other diseases used for microanalysis and determination of uranium dioxide and organic synthesis, also used as preservative, etc. used for drip analysis of uranium dioxide; used for measuring free acid in gastric juice organic synthesis raw materials; preservative; reagent for measuring free acid in gastric juice; drip analysis of uranium dioxide. Antipyretic analgesics and antirheumatic drugs. |
production method | add salicylic acid and sodium bicarbonate into distilled water, keep the temperature at 60 ℃, and keep it in an acidic state, and add appropriate amount of ethylenediaminetetraacetic acid (EDTA) and sodium hydrosulfite at the same time. Raise the temperature to 85 ℃ and react for half an hour. The qualified reaction solution is filtered into a boiling bed and dried at 85°C to obtain salicylic acid. |
spontaneous combustion temperature | >250°C |